Factor II Deficiency..
(Prothrombin)

Only 30 cases of this hereditary clotting factor defect have been identified in the whole world. It may take the form of a deficiency of prothrombin or an abnormal Factor II molecule. Either form may lead to severe bruising, excessive menstrual bleeding, postoperative hemorrhage, and occasionally muscle hematomas.

Mild cases may be treated with plasma infusion. Severe Factor II deficiencies may be treated with prothrombin complex concentrates (PCCs).

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